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ACR50: Up to 47% response achieved at Week 42 in biologic-naive patients

alt text — **In Future 5**

FUTURE 42 uncontrolled exploratory analysis: Nonresponder imputation.

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FUTURE 5 uncontrolled exploratory analysis: Nonresponder imputation.

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FUTURE 5 uncontrolled exploratory analysis: Nonresponder imputation.

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FUTURE 5 uncontrolled exploratory analysis: Nonresponder imputation.

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FUTURE 5 uncontrolled exploratory analysis: Nonresponder imputation.

Footnote: FUTURE 5 uncontrolled exploratory analy sis: Nonresponder imputate in a subgroup of biologic-naive patients from Week 1 to Week 24. No clinical or statistical conclusions can be drawn.4,5

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Important Safety Information

Do not use COSENTYX if you have had a severe allergic reaction to secukinumab or any of the other ingredients in COSENTYX. See the Medication Guide for a complete list of ingredients

COSENTYX is a medicine that affects your immune system. COSENTYX may increase your risk of having ses side effects such as:

Infections

COSENTYX may lower the ability of your immune system to fight infections and may increase your risk of infections.

Your doctor should check for tuberculosis (TB) before treatment with COSENTYX.

Do not use COSENTYX if you have had a severe allergic reaction to secukinumab or any of the other ingredients in COSENTYX. See the Medication Guide for a complete list of ingredients

COSENTYX is a medicine that affects your immune system. COSENTYX may increase your risk of having ses side effects such as:

Infections

COSENTYX may lower the ability of your immune system to fight infections and may increase your risk of infections.

Your doctor should check for tuberculosis (TB) before treatment with COSENTYX.

Test If your doctor feels that you are at risk for TB, you may be treated with medicine for TB before you b in treatment with COSENTYX and during treatment with COSENTYX.

Your doctor should watch you closely for signs and symptoms of TB during treatment with COSENTYX. Do not take COSENTYX if you have an active TB infection.

Before starting COSENTYX, tell your doctor if you:

are being treated for an infection
have an infection that does not go away or that keeps coming back
have TB or have been in close contact with someone with TB
think you have an infection or have symptoms of an infection, such as: fevers, sweats, or chills; muscle aches; cough; shortness of breath; blood in your phlegm; weight loss; warm, red, or painful skin or sores on your body; diarrhea or stomach pain; burning when you urinate or urinate more often than normal

After starting COSENTYX, call your doctor right away if you have any signs of infection

ACR50: Up to 47% response achieved at Week 42 in biologic-naive patients

In Future 5

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Tap for full Important Safety Information

Important Safety Information

Infections

Infections

Before starting COSENTYX, tell your doctor if you:

Indication Information